Research Article
Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach
Table 1
Extraction recovery and the matrix effect of diosgenin and IS on plasma determined by UPLC-MS/MS (n = 6).
| | Concentration (ng/ml) | Extraction recovery | Matrix effect | Mean (%) | RSD (%) | Mean (%) | RSD (%) |
| Diosgenin | 5 | 85.81 | 5.83 | 93.22 | 3.63 | | 50 | 86.66 | 6.49 | 92.36 | 4.12 | | 1000 | 100.27 | 5.75 | 93.07 | 3.47 |
| IS | 42 | 98.29 | 6.09 | 95.56 | 2.28 |
|
|