Journal of Analytical Methods in Chemistry

Review Article

Recent Advances and Perspectives on the Sources and Detection of Antibiotics in Aquatic Environments

Table 2

Summary of liquid chromatography-based conventional methods for the detection of antibiotics.


Conventional methods	Analytes	LOQ		LOD (ng/mL)	Reference
Conventional methods	Analytes	Lower limit	Upper limit	LOD (ng/mL)	Reference

HPLC-RLS	Enoxacin	NA	NA	5.1	[67]
	Ofloxacin	NA	NA	3.1
	Lomefloxacin	NA	NA	4.2
	Gatifloxacin	NA	NA	3.8
	Sparfloxacin	NA	NA	17.5

HPLC-DAD	Sulfonamide	NA	NA	0.54∼3.67	[68]
LC-MS/MS	Macrolide	3.0 ng/L	40.0 ng/L	10⁻³∼1.5 × 10⁻²	[46]
HPLC-UV	Fluoroquinolones	NA	NA	0.3∼1.4	[69]
HPLC-FLD	Fluoroquinolones	NA	NA	1.4 × 10⁻⁴∼6.1 × 10⁻⁴	[70]

HPLC-RLS: high-performance liquid chromatography-tandem resonance light scattering; DAD: diode array detector; UV: ultraviolet detection; FLD: fluorescence detector; LC‐MS/MS: liquid chromatography with tandem mass spectrometry; LOQ: limit of quantification (upper and lower limits of the method are extremes of the linear range of the method); NA: not available.