A Human Oral Fluid Assay for D- and L- Isomer Detection of Amphetamine and Methamphetamine Using Liquid-Liquid Extraction

Table 10

Concomitant medications: the indicated medications prepared in methanol were spiked into a QC 7.5 standard and measured. The data indicates percent difference from a QC standard spiked with blank methanol at the same volume as the drug standards.

Drug/Metabolite	% diff from MEOH spike
	Dextromethorphan	Phenylephrine	Diphenhydramine	Salicylic acid	Phentermine	OTC mix
Amphetamine	−0.92	−0.06	−0.84	1.89	−0.06	1.39
Methamphetamine	6.15	3.95	6.10	2.67	−2.29	−1.34
D-amphetamine	−0.77	−1.64	−2.00	1.06	−0.94	−3.90
L-amphetamine	−1.97	−0.41	2.07	1.30	3.21	−0.54
D-methamphetamine	−6.26	5.53	−6.10	−3.81	7.45	−5.96
L-methamphetamine	−2.10	−0.24	−0.08	0.71	7.73	−0.12