Journal of Analytical Methods in Chemistry

Research Article

Quantitative Analysis of Multicomponents in Qufeng Zhitong Capsule and Application of Network Pharmacology to Explore the Anti-Inflammatory Activity of Focused Compounds

Table 1

Characterization of chemical components from QZC by UHPLC/Q-Orbitrap-MS.


Peak no.	t_R (min)	Formula	ES⁺ (m/z)	ES⁻ (m/z)	Identification	Source

1	1.97	C₇H₆O₅	—	169.01329	Gallic acid	HG
2	3.93	C₇H₆O₄	—	153.0186	Protocatechuic acid	HG
3	5.84	C₁₆H₁₈O₉	355.10245	353.0878	Neochlorogenic acid	RD, HV
4	9.32	C₁₆H₁₈O₉	355.10239	353.08841	Chlorogenic acid	RD, FC, HV
5	10.63	C₁₆H₁₈O₉	355.10245	353.08762	Cryptochlorogenic acid	RD, HV
6	10.74	C₁₆H₂₄O₁₀	—	375.12973	Loganic acid	RD
7	12.92	C₂₇H₂₂O₁₈	—	633.07214	Corilagin	HG
8	15.42	C₁₈H₂₈O₁₂	—	435.15176	Loganin	RD
9	19.47	C₂₅H₂₄O₁₂	—	515.11908	Isochlorogenic acid B	RD, ReRC
10	19.91	C₂₅H₂₄O₁₂	—	515.11902	Isochlorogenic acid A	RD
11	22.6	C₂₅H₂₄O₁₂	—	515.11896	Isochlorogenic acid C	RD
12	26.3	C₂₀H₂₄O₇	—	377.15918	Angelol A	RAP
13	28.75	C₁₆H₁₆O₅	289.10638	—	Columbianetin acetate	RAP
14	32.22	C₄₇H₇₆O₁₈	—	973.50336	Akebia saponin D	RD
15	32.64	C₁₅H₁₆O₃	245.11714	—	Osthole	RAP
16	33.08	C₁₉H₂₀O₅	329.13821	—	Columbianadin	RAP

Compared with reference standards.