Research Article

Pharmacokinetic Study of Coadministration with Cefuroxime Sodium for Injection Influencing ReDuNing Injection-Derived Seven Phytochemicals and Nine Metabolites in Rats

Table 3

The regression equations, linear ranges, LLODs, and LLOQs of the seven analytes and cefuroxime.

AnalyteCalibration curvesCorrelation coefficientRange (ng/mL)LLOD (ng/mL)LLOQ (ng/mL)

Geniposidey = 0.0165x−0.00480.999662–619048.525.4
Shanzhisidey = 0.0688x + 0.00310.99948–77860.82.3
Genipin-1-β-gentiobiosidey = 0.0163x + 0.03270.999525–249522.16.6
Secoxyloganiny = 0.1029x + 0.02410.999326–257521.65.9
Neochlorogenic acidy = 0.0551x + 0.05180.999425–251904.38.2
Chlorogenic acidy = 0.0883x + 0.04180.999330–300004.613.3
Cryptochlorogenic acidy = 0.1215x + 0.03860.999422–217522.77.4
Cefuroximey = 0.0504x + 0.05260.9990557–55700016.447.5