Pharmacokinetic Study of Coadministration with Cefuroxime Sodium for Injection Influencing ReDuNing Injection-Derived Seven Phytochemicals and Nine Metabolites in Rats

Table 2

The experimental design of pharmacokinetic studies.

Group	1-D	2-D	3-D	4-D	5-D
1 (RDN-1)	—	—	—	—	a
2 (CNa-1)	—	—	—	—	b
3 (RDN/CNa-1)	—	—	—	—	a + b
4 (RDN-5)	a	a	a	a	a
5 (CNa-4 + RDN-1)	b	b	b	b	a
6 (RDN/CNa-4 + RDN-1)	a + b	a + b	a + b	a + b	a
7 (CNa-5)	b	b	b	b	b
8 (RDN/CNa-5)	a + b	a + b	a + b	a + b	a + b

a = RDN 2 mL/kg b = CNa 225 mg/kg.