Quantitative Analysis of the Multicomponent and Spectrum–Effect Correlation of the Antispasmodic Activity of Shaoyao-Gancao Decoction

Table 6

Effect of 15 batches of SGD on the contractile activity of isolated intestinal preparation (X ± SME, n = 6).

Batch	Average tension (g)					Inhibition rate (%)
	Control group	Ach model group	Drug administration group (15 mg/mL)	Drug administration group (25 mg/mL)	Drug administration group (35 mg/mL)	Drug administration group (25 mg/mL)	Drug administration group (35 mg/mL)
S1	0.4483 ± 0.04920	1.426 ± 0.1244^##	1.341 ± 0.0984	0.6487 ± 0.0472	0.4776 ± 0.0430	78.02 ± 5.549	97.05 ± 4.003
S2	0.5204 ± 0.01452	1.168 ± 0.1892^#	1.194 ± 0.1848	0.6943 ± 0.1398	0.4543 ± 0.06812	82.90 ± 12.32	120.3 ± 9.962
S3	0.4285 ± 0.03723	1.216 ± 0.1397^##	0.9784 ± 0.1218	0.5199 ± 0.05595	0.3260 ± 0.02184	88.08 ± 3.246	114.2 ± 2.65
S4	0.5635 ± 0.06599	1.914 ± 0.3118^##	1.703 ± 0.2831	0.8390 ± 0.07993	0.5414 ± 0.05365	86.11 ± 9.202	111 ± 8.952
S5	0.4279 ± 0.06277	1.358 ± 0.1667^##	1.160 ± 0.1562	0.5640 ± 0.08049	0.4190 ± 0.06737	84.74 ± 5.133	101.6 ± 2.695
S6	0.5296 ± 0.04119	1.159 ± 0.09607^##	0.9905 ± 0.09806	0.6552 ± 0.05702	0.5028 ± 0.03212	82.45 ± 5.394	103.9 ± 3.426
S7	0.4323 ± 0.06757	1.124 ± 0.1909^##	0.7886 ± 0.05031	0.3899 ± 0.03225	0.2655 ± 0.0438	99.13 ± 9.353	120.2 ± 7.817
S8	0.5116 ± 0.04533	0.9918 ± 0.05947^##	1.001 ± 0.03622	0.7059 ± 0.02238	0.5774 ± 0.01672	58.10 ± 8.560	85.36 ± 7.416
S9	0.4842 ± 0.05229	1.063 ± 0.1186^#	0.984 ± 0.2091	0.6202 ± 0.09016	0.3968 ± 0.0398	75.91 ± 7.580	113.4 ± 6.972
S10	0.4960 ± 0.05865	1.409 ± 0.1962^##	0.9719 ± 0.08651	0.4914 ± 0.04814	0.368 ± 0.05182	104.2 ± 5.288	120.4 ± 10.35
S11	0.3607 ± 0.04392	0.9241 ± 0.1457^##	0.5863 ± 0.07636	0.3203 ± 0.04721	0.2587 ± 0.05415	110.2 ± 4.840	117.5 ± 10.68
S12	0.3917 ± 0.03975	1.433 ± 0.2150^##	1.249 ± 0.2104	0.6738 ± 0.1062	0.4462 ± 0.07728	75.15 ± 5.218	98.39 ± 5.121
S13	0.5547 ± 0.09259	1.113 ± 0.1566^#	0.9223 ± 0.1112	0.5019 ± 0.0944	0.4470 ± 0.09103	107.4 ± 7.044	118 ± 6.441
S14	0.4113 ± 0.03592	0.8625 ± 0.08512^##	0.6173 ± 0.05789	0.3951 ± 0.03806	0.3036 ± 0.02892	108.9 ± 7.633	127.4 ± 5.618
S15	0.4967 + 0.02877	1.243 ± 0.2305^#	1.117 ± 0.2264	0.7182 ± 0.1251	0.5096 ± 0.06343	67.52 ± 9.100	94.27 ± 5.152

Compared with the control group: ; ; compared with the Ach model group: ; .