Simultaneous Assay of Dexchlorpheniramine Maleate, Betamethasone, and Sodium Benzoate in Syrup by a Reliable and Robust HPLC Method

Table 5

Results of accuracy.

Spiked level (%)	Replicate number	Dexchlorpheniramine maleate			Sodium benzoate			Betamethasone
		Spiked amount of standard (mg)	Peak area (mAU·s)	Recovery (%)	Spiked amount of standard (mg)	Peak area (mAU·s)	Recovery (%)	Spiked amount of standard (mg)	Peak area (mAU·s)	Recovery (%)
80%	1	1.606	2326791	99.7	7.895	5013454	101.6	0.199	695365	100.5
	2	1.606	2334539	100.0	7.895	4991733	101.2	0.199	703190	101.6
	3	1.606	2327665	99.7	7.895	5017325	101.7	0.199	696949	100.7
	Mean			99.8			101.5			100.9
	RSD (%)			0.2			0.3			0.6
100%	1	2.008	2890627	99.1	9.869	6225259	101.0	0.249	867571	100.3
	2	2.008	2899677	99.4	9.869	6238642	101.2	0.249	871281	100.8
	3	2.008	2885840	98.9	9.869	6216278	100.8	0.249	863282	99.8
	Mean			99.1			101.0			100.3
	RSD (%)			0.2			0.2			0.5
120%	1	2.409	3480064	99.4	11.843	7478069	101.1	0.298	1048690	101.1
	2	2.409	3469911	99.1	11.843	7470749	101.0	0.298	1047360	100.9
	3	2.409	3476467	99.3	11.843	7477084	101.1	0.298	1047448	100.9
	Mean			99.3			101.1			101.0
	RSD (%)			0.1			0.1			0.1