A Pyridazine-Based Fluorescent Probe Targeting Aβ Plaques in Alzheimer’s Disease

Scheme 1

Reaction scheme for the synthesis of the pyridazine-based probe (3). (i) DMF, 3,4-dihydroxybenzaldehyde, K₂CO₃, refluxed for 24 h; (ii) CHCl₃, cyanoacetic acid, piperidine, refluxed for 15 h.