Capture-SELEX: Selection of DNA Aptamers for Aminoglycoside Antibiotics

Figure 8

Potential assay strategies using aptamers selected by the Capture-SELEX principle. The switch from the hybridized to the dehybridized stage of the aptamers after target addition can be used to generate a recordable signal based on fluorometric methods like changes in fluorescence intensities, fluorescence resonance energy transfer (FRET), FRET with molecular beacon formation, or fluorescence polarization (FP).