Journal of Allergy / 2015 / Article / Tab 2

Review Article

Twin Studies of Atopic Dermatitis: Interpretations and Applications in the Filaggrin Era

Table 2

Population-based twin studies of the association between atopic dermatitis and asthma.

StudyCountryAge
(years)

(pairs)
Phenotypic correlationProportion due to genetic factors (%)Diagnostic method

Lichtenstein and Svartengren (1997) [10]Sweden7–913390.3085Parent-report
Thomsen et al. (2006) [15]Denmark12–41112310.4081Self-report
van Beijsterveldt and Boomsma (2007) [16]Netherlands586330.5582Parent-report

Phenotypic correlation is the correlation between the individual liabilities to atopic dermatitis and asthma.
Proportion due to genetic factors is the proportion of phenotypic correlation explained by genetic factors shared between atopic dermatitis and asthma.

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