Noninterventional Open-Label Trial Investigating the Efficacy and Safety of Ectoine Containing Nasal Spray in Comparison with Beclomethasone Nasal Spray in Patients with Allergic Rhinitis

Table 3

Development of ear/palate itching during the study (d1 to d14 or V1 to V2) as assessed by patients and investigators. The total number of patients (% given in brackets) where symptoms were reduced, unchanged, or deteriorated is shown.

Ear/palate itching	Patients’ assessment		Total	Physicians’ assessment		Total
	Group 1	Group 2		Group 1	Group 2
Reduced	4 (17.4%)	12 (48.0%)	16 (33.3%)	12 (48.0%)	14 (56.0%)	26 (52.0%)
Unchanged	14 (60.9%)	9 (36.0%)	23 (47.9%)	12 (48.0%)	8 (32.0%)	20 (40.0%)
Deteriorated	5 (21.7%)	4 (16.0%)	9 (18.8%)	1 (4.0%)	3 (12.0%)	4 (8.0%)
Total	23 (100.0%)	25 (100.0%)	48 (100.0%)	25 (100.0%)	25 (100.0%)	50 (100.0%)
Fisher’s exact test	𝑃=𝟎.𝟎𝟖𝟖			𝑃=𝟎.𝟑𝟓𝟕