Review Article

Breed-Predispositions to Cancer in Pedigree Dogs

Table 4

Patterns of excess lymphoma by breed and age, comparing the observed numbers of lymphoma cases per breed, over four (quartile) age ranges, with expected numbers computed from age incidence.

Age ≤ 34 ≤ Age ≤ 67 ≤ Age ≤ 910 ≤ Age ≤ 14 No dogs by breed
O E O E O E O E

Border collie 1 0.37 0 0.47 1 0.68 1 0.93 2378
Boxer 1 1.06 2 1.05 0.75 0.52 5628
Bulldog 0.38 0 0.24 0 0.10 0 0.006 1720
Bullmastiff 0 0.21 0.17 0 0.09 0 0.016 1075
CKCS 0 0.71 1 1.15 2 1.08 0 0.85 4529
Cocker spaniel 0 0.95 1 1.16 1 1.06 0 0.90 5568
Crossbred 2 1.01 1 2.06 4 4.03 4 5.13 8855
Dalmatian 1 0.37 0 0.34 0 0.20 0 0.20 1973
Doberman 1 0.34 0 0.30 0 0.43 1 0.54 2006
English springer spaniel 0 0.72 0 0.87 1 0.89 3 0.93 4308
German shepherd dog 0 2.14 1 2.36 1 2.33 1 1.82 12157
Golden retriever 1.02 3 2.78 1 2.40 6 2.86 11348
Irish setter 0 0.16 0.31 0 0.22 0 0.26 1123
Labrador retriever 2 2.84 2 3.20 2 2.89 1 3.02 16259
Miniature schnauzer 0 0.17 0 0.20 1 0.18 0 0.16 1007
Old English sheepdog 0 0.18 1 0.29 1 0.27 0 0.26 1086
Rottweiler 0 0.45 0 0.32 2 0.44 0 0.38 2446
Staffordshire bull terrier 0 0.51 0 0.39 1 0.47 1 0.38 2844
West Highland white terrier 0 1.07 0 1.15 0 0.99 1 0.81 6134
Other breeds 6 6.5 11 8.22 5 7.48 5 7.05 38240

Total 130684

O: observed, E: expected.
Individually P ≤ 0.01 by Poisson distribution.
Individually P ≤ 0.001 by Poisson distribution.
Individually P ≤ 0.05 by Poisson distribution.
Table from [158].