Review Article
Ehlers-Danlos Syndrome, Hypermobility Type: An Underdiagnosed Hereditary Connective Tissue Disorder with Mucocutaneous, Articular, and Systemic Manifestations
Table 3
The Brighton criteria for JHS.
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Adapted from [9]. Note 1: criteria major 1 and minor 1 are mutually exclusive as are major 2 and minor 2. Note 2: for the diagnosis of the joint hypermobility syndrome: both major, or 1 major and 2 minor, or 4 minor criteria, or 2 minor criteria and one or more first-degree affected relative(s). Note 3: diagnosis of joint hypermobility syndrome needs previous (clinical/molecular) exclusion of other overlapping heritable connective tissue disorders, such as Marfan syndrome and other Ehlers-Danlos syndrome subtypes. |