C-Peptide Reduces Mitochondrial Superoxide Generation by Restoring Complex I Activity in High Glucose-Exposed Renal Microvascular Endothelial Cells
Figure 1
(a) State 3 respiration is the slope of measured O2 consumption in the presence of glutamate-malate and ADP. *, significantly different than low-glucose and high-glucose + C-peptide (). (b) State 4 respiration is the slope of measured O2 consumption after ADP depletion. (c) RCR is the ratio of state 3 to state 4 respiration. *, significantly less than low-glucose and high-glucose + C-peptide (*). experiments. Data represent mean SEM.
