Effectiveness of Antimicrobial Stewardship Program in Long-Term Care: A Five-Year Prospective Single-Center Study

Table 2

Effect of time and unit on the number of isolated multidrug-resistant organisms in hospital-acquired infections from 2015 to 2020.

Effect	Wilk’s lambda	value	Effect size (squared Eta)	Interpretation
Time (year)	0.311	0.008	0.689	The effect of time explained 68.9% of the variability in the number of isolated MDRs in HAI
Unit	-	0.071	0.189	The effect of the unit alone was not significant to explain the variability in the number of isolated MDRs in HAI
Timeunit	0.409	0.036	0.591	The effect of the timeunit explained 59.1% of the variability in the number of isolated MDRs in HAI

MDR: multidrug-resistant; HAI: hospital-acquired infections; Multifactorial Repeated-Measure ANOVA analyzing the effect of time (year) and unit (intensive care unit versus long-term care) on the change in the raw number of multidrug-resistant organisms isolated in hospital-acquired infections, from the start of the antimicrobial stewardship program in 2015 to 2020. The yearly estimated marginal means are depicted by the unit in Figure 6. Squared Eta >0.14 indicates a large effect. Statistically significant result ().