Effectiveness of Antimicrobial Stewardship Program in Long-Term Care: A Five-Year Prospective Single-Center Study

Table 1

Change in antibiotics defined daily doses per 1,000 patient days following the implementation of the antimicrobial stewardship program.

Antibiotic	Defined daily dose per 1,000 patient days
	2015	2016	2017	2018	2019	2020
Meropenem	26.1	79.9	71.8	82.7	80.3	92.0
Imipenem	46.4	33.5	14.3	0.0	0.0	0.0
Piperacillin/Tazobactam	67.5	64.8	27.5	25.7	35.5	46.2
Colistin	24.6	34.6	22.0	19.5	15.1	15.5
Caspofungin	12.3	4.4	15.1	9.5	14.6	1.4
Levofloxacin	24.6	5.2	3.3	4.1	1.3	0.9
Linezolid	5.1	3.2	3.6	2.9	0.5	0.6
Amikacin	19.2	19.3	14.6	10.2	9.5	13.6
Tigecycline	20.4	6.6	116.6	2.2	3.2	1.7
Cefepime	10.6	10.2	8.5	0.2	2.0	2.7
Overall (average)	25.7	26.2	29.7	15.7	16.2	17.5