Epidemiology of Pediatric Tuberculosis and Factors Associated with Unsuccessful Treatment Outcomes in the Centre Region of Cameroon: A Three-Year Retrospective Cohort Study

Table 4

Factors associated with unsuccessful treatment outcome.

Demographic and clinical factors	Univariate analysis		Multivariate analysis
	COR (95% CI)	-value	AOR (95% CI)	-value
Residence
Rural	0.63 (0.38–1.05)	0.082	0.70 (0.41–1.22)	0.208
Urban	1	1
Type of TB
Extra pulmonary TB	2.02 (1.20–3.41)	0.008	1.31 (0.41–4.24)	0.588
PTB−	2.81 (1.71–4.62)	<0.001	1.41 (0.44–4.47)	0.554
PTB+	1	1
Method of diagnosis
Clinical diagnosis	2.29 (1.46–3.57)	<0.001	2.46 (1.55–3.91)	<0.001
Bacteriological diagnosis	1	1
HIV status
HIV-positive	2.25 (1.45–3.49)	<0.001	2.43 (1.55–3.80)	<0.001
Unknown	0.31 (0.15–0.62)	0.001	0.32 (0.16–0.64)	0.001
HIV-negative	1	1
Treatment protocol
Pediatric regimen (2RHEZ + 4RH)	1	1	0.172
Adult regimen (2RHEZ + 4RH)	1.61 (1.06–2.42)	0.023	0.73 (0.46–1.14)
Year of TB initiation
2018	1.61 (1.00–2.57)	0.048	1.25 (0.78–1.87)	0.311
2019	1.32 (0.80–2.15)	0.282	1.32 (0.80–2.15)	0.368
2020	1	1