Research Article

Extended-Spectrum β-Lactamase (ESBL) Genotypes among Multidrug-Resistant Uropathogenic Escherichia coli Clinical Isolates from a Teaching Hospital of Nepal

Table 3

Antibiotic susceptibilities of ESBL-producing and nonproducing uropathogenic E. coli isolates.

AntimicrobialsEscherichia coli urinary isolates
TotalESBL producers (n = 62)ESBL nonproducers (n = 92)
Susceptible (%)Susceptible (%)Susceptible (%)

Ampicillin18 (11.7)0 (0.0)16 (17.3)0.005
Piperacillin48 (31.1)8 (12.9)40 (43.4)≤0.001
Cefixime78 (50.6)0 (0.0)78 (84.8)≤0.001
Cefotaxime82 (53.2)4 (6.4)78 (84.8)≤0.001
Ceftazidime84 (54.5)4 (6.4))80 (86.9)≤0.001
Gentamycin118 (76.6)50 (80.6)68 (73.9)0.220
Cotrimoxazole80 (51.9)32 (51.6)48 (52.1)0.538
Nitrofurantoin142 (92.2)56 (90.3)86 (93.4)0.336
Ofloxacin90 (58.4)22 (35.4)68 (73.1)≤0.001
Imipenem146 (94.8)56 (90.3)90 (97.8)0.047
Meropenem136 (88.3)52 (83.8)84 (91.3)0.018