Predictors of Major Bleeding and Mortality in Dengue Infection: A Retrospective Observational Study in a Tertiary Care Centre in South India

Table 4

Predictors of mortality.

Outcome	Mortality		value
	Yes	No
Age^§	47.3 (18.7)	30.9 (13.1)	0.016
Male (n = 96)	2	94	0.649
Days of fever^§	4.3 (2.2)	5.1 (2.2)	0.436
Rash (n = 59)	1	58	1.00
Myalgia (n = 96)	2	94	0.649
Arthralgia (n = 20)	1	19	0.419
Vomiting (n = 112)	3	109	1.00
Loose stools (n = 32)	0	32	0.584
Abdominal pain (n = 61)	2	59	0.638
Total leukocyte count (×10^9/L)^§	10.4 (5)	5.9 (3.6)	0.015
Platelet count (×10^3/μL)^§	33 (36)	59 (65)	0.424
Creatinine (μmol/L)^§	109 (61)	67.9 (29)	0.009
Total bilirubin (μmol/L)^§	37.1 (22.2)	14.9 (20.5)	0.029
SGOT (serum glutamic oxaloacetic transaminase) (U/L)^§	4831 (7833)	304 (652)	0.0001
SGPT (serum glutamic pyruvic transaminase) (U/L)^§	1768 (2495)	164 (309)	0.0001
SOFA^a score^§	7.25 (3.4)	3.16 (1.6)	0.0001
Major bleed (n = 108)	2	49	0.594
Late dengue (n = 39)	13	26	1.00
Severe dengue (n = 69)	2	67	1.00
Secondary dengue^⋄ (n = 121)	4	117	0.573

^aSOFA, sequential organ failure assessment; ^§mean (standard deviation); value < 0.05 indicates a statistically significant association; late dengue indicates presentation after 5 days of symptom onset; ^⋄secondary dengue has both IgG and IgM antibodies positive, while primary dengue has IgM and/or NS1 antigen positive.