Research Article

Assessing the Impact of Isoniazid Preventive Therapy (IPT) on Tuberculosis Incidence and Predictors of Tuberculosis among Adult Patients Enrolled on ART in Nekemte Town, Western Ethiopia: A Retrospective Cohort Study

Table 2

Baseline clinical, laboratory results, and followup outcome characteristics of PLWH at Nekemte referral hospital and Nekemte Health center followed from September 2009-September 2012.

Variables(n=600)CategoryCohort groupTotal n (%)
IPT n (%) cohortNon-IPT cohort n (%)ā€‰

CD4<=20020(10%)68(11.33%)88(14.66%)
201-35064(32%)119(29.75%)183(30.5%)
351-50052(26%)97(24.25%)149(24.83%)
>50064(32%)116(29%)180(30%)

BMI>=18.5127(63.5%)229(57.25%)356(59.33%)
<18.573(36.5%)171(42.75%)244(40.66%)

Weight<=5085(42.5%)177(44.25%)266(40.66%)
>50115(57.5%)223(55.75%)338(56.33%)

WHO StageI/II164(82%)294(73.5%)458(76.33%)
III/IV36(18%)106(26.5%)142(23.66%)

Functional StatusWorking169(84.5%)348(87%)517(86.16%)
Ambulatory/Bedridden29(14.5%)43(10.75%)72(18%)

Opportunistic InfectionYes45(22.5%)80(20%)125(20.83%)
No155(77.5%)320(80%)475(79.16%)

Cotrimoxazole TreatmentYes142(71%)287(71.75%)429(71.5%)
No58(29%)113(28.25%)171(28.5%)

Previous TBYes45(22.5%)80(20%)125(20.83%)

ā€‰No155(77.5%)320(80%)475(79.16%)

Outcome statusTB11(5.5%)42(10.5%)53(8.83%)
Censored189(94.5%)358(89.5%)547(91.16%)

Censored: loss to followup, death, transferred out, started IPT (for non-IPT).