Research Article

Combining Microarray Technology and Molecular Epidemiology to Identify Genes Associated with Invasive Group B Streptococcus

Table 1

Sensitivity (probability open reading frame is detected, given it is truly present) and specificity assessments (probability open reading frame is not detected, given it is not present) of different cutoff values in classifying variable open reading frames using fine-tiling oligonucleotide genome arrays created from the genomic sequence of group B Streptococcus strains NEM316 and 2603VR.

Reference genomePercentage cutoff pointSensitivitySpecificity

NEM31620%0.980.91
15%0.970.94
10%0.960.96

2603VR20%0.970.91
15%0.950.92
10%0.890.96