Simple Atomic Absorption Spectroscopic and Spectrophotometric Methods for Determination of Pioglitazone Hydrochloride and Carvedilol in Pharmaceutical Dosage Forms
Table 8
Evaluation of the interday and intraday precision and accuracy for PGZ-HCl and CRV obtained by Method B.
Drug
Method
Taken conc. (gmL−1)
Interday
Intraday
Recovery (%)a
Precision (RSD%)a
Accuracy (Er%)
Recovery (%)a
Precision (RSD%)a
Accuracy (Er%)
PGZ-HCl
Fast green
1
98.94
1.80
−1.06
99.24
1.03
−0.76
2
99.55
1.09
−0.45
99.97
0.95
−0.03
3
100.13
0.78
0.13
98.65
1.17
−1.35
Orange G
10
99.41
1.31
−0.59
98.71
1.19
−1.29
30
101.45
0.98
1.45
99.89
1.17
−0.11
60
99.08
1.13
−0.92
101.65
0.96
1.65
CRV
Fast green
1
98.88
1.21
−1.12
98.56
1.23
−1.44
2
101.76
0.86
1.76
99.87
1.38
−0.13
3
99.68
1.49
−0.32
98.78
1.17
−1.22
Orange G
10
100.43
1.31
0.43
100.57
1.14
0.57
25
98.13
0.87
−1.87
101.67
1.26
1.67
40
99.87
1.34
−0.13
101.99
0.87
1.99
RSD%: percentage relative standard deviation. Er%: percentage relative error.
aMean of five trials of determination.