Simple Atomic Absorption Spectroscopic and Spectrophotometric Methods for Determination of Pioglitazone Hydrochloride and Carvedilol in Pharmaceutical Dosage Forms

Table 6

Results of the analysis for determination of PGZ-HCl and CRV (authentic) using Method B.

Parameters	PGZ-HCl*						CRV*
	Fast green FCF method			Orange G method			Fast green FCF method			Orange G method
	Taken; 𝜇gmL^−1	Found; 𝜇gmL^−1	Recovery; %	Taken; 𝜇gmL^−1	Found; 𝜇gmL^−1	Recovery; %	Taken; 𝜇gmL^−1	Found; 𝜇gmL^−1	Recovery; %	Taken; 𝜇gmL^−1	Found; 𝜇gmL^−1	Recovery; %
	0.5	0.51	101.18	10	10.02	100.21	0.5	0.50	99.66	5	5.01	100.19
	1	0.99	99.43	20	20.02	100.10	1	1.00	99.50	10	10.01	100.10
	1.5	1.51	100.57	30	29.81	99.37	1.5	1.50	100.07	20	19.86	99.32
	2	1.98	99.07	40	39.95	99.88	2	2.01	100.36	25	25.25	101.01
	2.5	2.51	100.24	50	50.44	100.88	2.5	2.51	100.41	30	30.11	100.36
	3	3.00	99.98	60	60.23	100.38	3	2.99	99.60	40	40.01	100.02
	4	4.00	100.05	70	69.74	99.63				45	45.06	100.13
Mean			100.08			100.07			99.93			100.16
±SD			0.70			0.50			0.40			0.50
±RSD			0.70			0.50			0.40			0.50
±SE			0.26			0.19			0.16			0.19
Variance			0.49			0.25			0.16			0.25
Slope			0.1945			0.0143			0.3201			0.0206
LOD; 𝜇gmL^−1			0.13			0.23			0.078			0.16
LOQ; 𝜇gmL^−1			0.39			0.7			0.24			0.49
Sandell’s; sensitivity; 𝜇gcm^−2			0.0036			0.078			0.0032			0.046
Apparent Molar; absorptivity; LMol^−1cm^−1		10.87×10^4		0.50×10^4			12.83×10^4			0.88×10^4

∗Average of three different trials of determination.