Simple Atomic Absorption Spectroscopic and Spectrophotometric Methods for Determination of Pioglitazone Hydrochloride and Carvedilol in Pharmaceutical Dosage Forms

Table 5

Analytical parameters for the determination of PGZ-HCl and CRV via Method B.

Parameters	PGZ-HCl		CRV
	Fast green FCF	Orange G	Fast green FCF	Orange G
Conc. of reagent, w/v	0.01%	0.4%	0.01%	0.2%
Vol. of reagent, mL	1	0.5	1	0.5
𝜆max, nm	631	498	631	498
Beer's law limits 𝜇gmL^−1	0.5–4	10–70	0.5–3	5–45
Regression equation*
Intercept	0.1116	−0.0413	−0.0055	0.0168
Slope	0.1945	0.0143	0.3201	0.0206
Correlation Coefficient	0.9999	0.9999	0.9999	0.9999
Molar Ratio	2 : 3	1 : 1	1 : 1	1 : 1
^∗𝐴=𝑎+𝑏 𝐶, where 𝐶 is the concentration of drug in 𝜇gmL^−1, 𝐴 is the absorbance,; 𝑎 is the intercept, and 𝑏 is the slope.