Research Article
New Kinetic Spectrophotometric Method for Determination of Fexofenadine Hydrochloride in Pharmaceutical Formulations
Table 3
Accuracy and precision for the determination of FEX in bulk powder by the proposed initial rate and fixed time methods.
| Method | FEX, g mL−1 | RSD% |
Confidence limit (P = 0.05; n = 6) | Recovery% | Taken | Founda | SD |
| Initial rate | 5.00 | 5.01 | 0.12 | 2.39 | 5.01 ± 0.13 | 100.20 | 20.00 | 20.20 | 0.20 | 0.99 | 20.20 ± 0.22 | 101.00 | 35.00 | 34.90 | 0.28 | 0.80 | 34.90 ± 0.31 | 99.71 | 50.00 | 50.13 | 0.14 | 0.28 | 50.13 ± 0.15 | 100.26 |
| Fixed time | 5.00 | 5.04 | 0.13 | 2.58 | 5.04 ± 0.15 | 100.80 | 20.00 | 20.14 | 0.30 | 1.49 | 20.14 ± 0.34 | 100.70 | 35.00 | 35.00 | 0.32 | 0.91 | 35.00 ± 0.36 | 100.00 | 50.00 | 50.31 | 0.36 | 0.71 | 50.31 ± 0.40 | 100.62 |
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Average of six determinations.
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