New Kinetic Spectrophotometric Method for Determination of Fexofenadine Hydrochloride in Pharmaceutical Formulations

Table 3

Accuracy and precision for the determination of FEX in bulk powder by the proposed initial rate and fixed time methods.

Method	FEX, 𝜇g mL^−1			RSD%	Confidence limit; (P = 0.05; n = 6)	Recovery%
	Taken	Found^a	SD
Initial rate	5.00	5.01	0.12	2.39	5.01 ± 0.13	100.20
	20.00	20.20	0.20	0.99	20.20 ± 0.22	101.00
	35.00	34.90	0.28	0.80	34.90 ± 0.31	99.71
	50.00	50.13	0.14	0.28	50.13 ± 0.15	100.26
Fixed time	5.00	5.04	0.13	2.58	5.04 ± 0.15	100.80
	20.00	20.14	0.30	1.49	20.14 ± 0.34	100.70
	35.00	35.00	0.32	0.91	35.00 ± 0.36	100.00
	50.00	50.31	0.36	0.71	50.31 ± 0.40	100.62

aAverage of six determinations.