Research Article

New Kinetic Spectrophotometric Method for Determination of Fexofenadine Hydrochloride in Pharmaceutical Formulations

Table 2

Analytical characteristics of the fixed time (15 min) method.

ParametersFEX

(nm)610
Beer’s law range ( g mL−1)2.5–50.0
Ringbom optimum concentration range ( g mL−1)10.0–40.0
Detection limit ( g mL−1)0.055
Quantification limit ( g mL−1)0.183
Molar absorptivity (L mol−1 cm−1)1.22 × 104
Stoichiometric relationship, FEX : KMnO41 : 1
Sandell’s sensitivity ( g cm−2 per 0.001 absorbance unit)0.088
Regression equationaA = 0.0209C + 0.024
Correlation coefficient, 0.9998

A = mC + b, where A is the absorbance and C is the concentration in g mL−1.