Review Article

Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth

Table 2

Diagnostic criteria for polycystic ovary syndrome.

Clinical or biochemical hyperandrogenismOligo/anovulationUS finding of polycystic ovaries*

NIH, 1990
Both of the following:
++

ESHRE/ASRM, 2003
Only 2 of the following:
+++

AES, 2006
All 3 of the following:
+++

NIH: National Institute of Health of the United States; ESHRE: European Society of Human Reproduction and Embryology; ASRM: American Society of Reproductive Medicine; AES: Androgen Excess and PCOS Society.
All sets of criteria require the exclusion of other etiologies such as congenital adrenal hyperplasia, androgen-secreting neoplasms, and Cushing’s síndrome.
Ultrasound polycystic ovaries can be defined as the presence of ≥12 follicles of 2–9 mm width or an increase in ovarian volume (>10 mL) in at least one ovary, in women not consuming oral contraceptives.