Research Article
Clinical and Autoimmune Profile of Scleroderma Patients from Western India
Table 4
Demographic and serological similarities/differences in Indian scleroderma patients in various regions across the country.
| Regions of India | | Western *Present, reference [15] | Northern Reference [10–12] | Southern Reference [13, 14] |
| Disease onset | | | | dsSSc | 40.9% | 94%, 88.1% | | IcSSc | 29.1% | 6%, 11.9% | | Cutaneous | | | | Skin thickening | 98.2% | | | Peripheral vascular | | | | Raynaud’s phenomenon | 68.2%, 83.3% | 92.9%, 60% | 17.3%, 28.2% | Digital ulcers and/or gangrene | 20.9% | | | Pulmonary | | | | Interstitial lung disease (ILD) | 88.2% | | | Pulmonary hypertension | 61.2% | | | Renal | 10.9%, 8.3% | 3.4%, 6%, 20% | 10.3% | Musculoskeletal | 39.1%, 54.2% | 36.7%, 80% | 66.7% | Gastrointestinal | 7.3%, 50% | | | Cardiovascular | 13.6%, 12.5% | | | Autoantibodies | | | | ANA | 85.5% | 89.1%, 70% | | Anti-Scl70 | 62.7% | 55.5% | | Anti-centromere | 22.7% | | |
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There are no published reports from Eastern part of the country.
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