Over the past few decades, natural and synthetic polymers have demonstrated promising applications as biomedical materials. Functional biomedical polymers are of specific interest, as they exhibit a wide variety of physical and chemical properties, allowing for the adjustment of biocompatibility, biodegradability, stimuli-responsiveness, and bioactivities. The current advancement of medical technology results in new requirements for multifunctional and adaptive polymer materials, which have to be addressed by appropriate schemes of synthesis and modification.

Functional polymer biomaterials could be easily processed into various device modalities, such as nanoparticles, nanofibers, microspheres, microfibers, hydrogels, membranes, and scaffolds. With different morphologies and versatile functionality, these polymer devices are showing considerable applications in almost all biomedical fields, including diagnosis, controlled delivery of therapeutic agents, efficient adjuvants of immunotherapy, regenerative medicine, and medical devices.

This Special Issue aims to provide a comprehensive collection of the latest advances in the development of preparation approaches, the mechanism underlying structure-property correlations, and the current and emerging biomedical applications of functional polymer-based materials. Original research papers and review articles are welcomed.

Potential topics include but are not limited to the following:

• Polymerization or postpolymerization modification
• Functionality and characterizations of polymers
• Functional polymers with biological activities (e.g., antitumor, antidiabetic, or antimicrobial activities)
• Processing of functional polymers
• Functional polymers for diagnosis
• Functional polymers for delivery of bioactive agents
• Functional polymers as adjuvant of immunotherapy
• Functional polymers for regenerative medicine (e.g., tissue engineering of bone, cartilage, nerve, and skin)
• Functional polymers for medical devices