|
Polymer | Property | Biomedical application | Trade name |
|
PGA | Regenerate biological tissue [121] | First biodegradable synthetic suture in 1969 | DEXON |
Good mechanical properties [122] | Bone internal fixation devices | Biofix |
|
PLLA | Good tensile strength | Orthopaedic fixation devices | Bio-Anchor, Meniscal Stinger, The Clearfix Meniscal Dart |
| Improved suture [123] | High-strength fibers (FDA approved at 1971) | DEXON |
| Nondegradable fibers [124] | Ligament replacement or augmentation devices | Dacron |
| Fiber-based devices [125] | Blood vessel conduits | |
| Injectable form | People with human immunodeficiency virus or correction of facial fat loss | |
|
PLDLA | Better property modulation [126] | Bioresorbable implant material | Resomer |
|
PLGA | High degradation | Multifilament suture | Vicryl, Vicryl Rapid & CRYL |
| Form of meshes | Skin graft | Vicryl Mesh |
|
PLGA-collagen | Matrix | Tissue regeneration membrane | CYTOPLAST Resorb |
|
PLGA | Prostate cancer | Drug delivery vehicle | LUPRON DEPOT |
| | First commercially developed monofilament suture (1980) | PDS |
|
PDS | Fixation screws for small bone and osteochondral fragments | Orthopaedic applications | Pins |
|
PCL | Long-term zero-order release [26] | Long-term contraceptive device | Capronor |
|
PDLLA-CL | Fibers less stiff | Monofilament suture | MONACRYL |
|
PGCL, PLCL, and PEG | Bioresorbable multiblock | Drug delivery vehicle for small, and medium-sized biologically active molecules | SynBiosys |
|
PCLTMC | multiblock | Flexible suture materials | Maxon |
and PGCL | | Orthopaedic tacks and screws | Acufex |
|
PHBHV | Piezoelectricity property [127] | Bone pins and plates and drug delivery | |
|
PEU | High porous & no adverse effect [128] | Tissue engineering application | Degrapol |
|
LDI-based PU | Injectable & good mechanical property [129] | Orthopaedic applications & bone cement | Polynova |
|
PEAs | Potential bioresorbable suture materials | Site-specific delivery of small hydrophobic drugs and peptides | CAMEO |
|
POE | Hydrophobic, surface eroding [130] | Drug delivery applications and ocular applications | Alzamer |
|
Polyanhydrides | Surface erosion & biocompatibility Evaluations [131] | Chemotherapeutic, brain cancer (FDA approved) | Gliadel |
|
PCA | Absorb or encapsulate a wide range of drug or protein molecules [132] | First biodegradable polymers used for developing nanoparticles for drug delivery application | |
| Synthetic surgical glue, skin adhesive, and an embolic material | Tissue adhesives for topical skin application (FDA approved) | Dermabond |
| Major component of skin and other musculoskeletal tissues [133] | Bilayer skin substitute (FDA approved) | Integra Dermal Regeneration Template |
| | Wound dressings | Biobrane &Alloderm |
|
Collagen | Scaffolds for cardiovascular, musculoskeletal & nervous tissue engineering [133] | Bioengineered skin equivalents | TransCyte |
|
HA | Promote angiogenesis [134] | Wound dressing application | HYAFF |
| Sponge as a carrier vehicle for osteoinductive protein [135] | Synthetic bone graft | OSSIGEL |
|
HMW viscous HA | Injectable soft tissue fillers [136] | Corneal transplantation and glaucoma surgery | AMVISC & AMVISC Plus |
|
Viscous HA | Synovial fluid substitute [137] | To relieve pain and improve join mobility in osteoarthritis patients | SYNVISC,ORTHOVISC |
|