Correlation between Saliva and Plasma Levels of Endothelin Isoforms ET-1, ET-2, and ET-3

Table 1

Plasma and saliva endothelin levels (mean ± SD) in male subjects.

	BET-1	ET-1	ET-2	ET-3	Total	BET-1/ET-3
Plasma (pmol/mL)
All (30)	3.35 ± 1.28	3.45 ± 1.28	1.63 ± 0.66	2.32 ± 1.44	10.8 ± 3.46	1.84 ± 1.00
18–40 years (19)	3.39 ± 1.38	3.22 ± 1.43	1.56 ± 0.61	1.97 ± 1.21	10.1 ± 3.7	2.10 ± 1.07
41–63 years (11)	3.29 ± 1.15	3.87 ± 0.89	1.77 ± 0.73	2.91 ± 1.67	11.8 ± 2.9	1.38 ± 0.70
Saliva (pmol/mL)
All (30)	0.55 ± 0.27	0.52 ± 0.21	0.21 ± 0.07	0.39 ± 0.19	1.68 ± 0.53	1.61 ± 0.75
18–40 years (19)	0.59 ± 0.32	0.56 ± 0.25	0.20 ± 0.07	0.37 ± 0.16	1.71 ± 0.64	1.68 ± 0.66
41–63 years (11)	0.49 ± 0.12	0.47 ± 0.13	0.23 ± 0.09	0.43 ± 0.23	1.62 ± 0.27	1.48 ± 0.91
Plasma/saliva
All (30)	6.94 ± 3.30	7.05 ± 2.58	8.18 ± 3.16	6.15 ± 2.34	6.67 ± 1.79
18–40 (19)	6.86 ± 3.50	6.11 ± 2.16	8.16 ± 3.18	5.71 ± 2.73	6.30 ± 1.93
41–63 (11)	7.07 ± 3.10	8.67 ± 2.51	8.22 ± 3.28	6.89 ± 1.25	7.31 ± 1.36

Note: value for comparison between the two age groups (-test or Mann-Whitney Rank Sum Test). The number of subjects is shown in parentheses.