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| General activity categories | Specific molecules | Cytogenetic location | Biologic activities |
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| Tissue factor pathway inhibitor; TFPI | 2q32.1 | Regulates the tissue factor-(TF-) dependent pathway of blood coagulation |
| Kininogen; KNG | 3q27.3 | Plays an important role in assembly of the plasma kallikrein |
| Growth arrest-specific 6; GAS6 | 13q34 | Stimulates cell proliferation |
| Multimerin; MMRN | 4q22 | Carrier protein for platelet factor V |
| Clotting factors and related proteins | Antithrombin; AT | 1q25.1 | Is the most important inhibitor of thrombin |
| Protein S; PROS1 | 3q11.1 | Inhibits blood clotting |
| Coagulation factor V; F5 | 1q24.2 | Acts as a cofactor for the conversion of prothrombin to thrombin by factor Xa |
| Coagulation factor XI; F11 | 4q35.2 | It participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the presence of calcium ions |
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| Plasminogen; PLG | 6q26 | Induces plasmin production (leads to fibrinolysis) |
| Plasminogen activator inhibitor 1; PAI1 | 7q22.1 | Regulation of plasmin production |
| Alpha-2-plasmin inhibitor | 17p13.3 | Inactivation of plasmin |
| Fibrinolytic factors and related proteins | Osteonectin; ON | 5q33.1 | Inhibits cell-cycle progression and influences the synthesis of extracellular matrix (ECM) |
| Histidine-rich glycoprotein; HRG | 3q27.3 | Interacts with heparin and thrombospondin |
| Thrombin-activatable fibrinolysis inhibitor; TAFI | 13q14.13 | Attenuates fibrinolysis |
| Alpha-2-Macroglobulin; A2M | 12p13.31 | Carrier of specific growth factors and induces cell signaling |
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| Tissue inhibitor of metalloproteinase 4; TIMP4 | 3p25.2 | Inhibits matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix |
| Complement component 1 inhibitor; C1NH | 11q12.1 | Inhibits serine proteinases including plasmin, kallikrein, and coagulation factors XIa and XIIa |
| Proteases and antiproteases | Alpha-1-antitrypsin (serpin peptidase inhibitor) | 14q32.13 | Acute phase protein, inhibits a wide variety of proteases and enzymes |
| Nexin 2; SNX2 | 5q23.2 | Modulates intracellular trafficking of proteins to various organelles |
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| Platelet factor 4; PF4 | 4q13.3 | Inhibition of angiogenesis |
| Basic proteins | β-thromboglobulin (Pro-platelet basic protein; PPBP) | 4q13.3 | Platelet activation, inhibition of angiogenesis |
| Endostatin (Collagen, type XVIII, Alpha-1; COL18A1) | 21q22.3 | Inhibitors of endothelial cell migration and angiogenesis |
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| Fibrinogen; FG | 4q31.3 | Blood clotting cascade (fibrin clot formation) |
| Fibronectin; FN | 2q35 | Binds to cell-surface integrins, affecting cell adhesion, cell growth, migration, and differentiation |
| Adhesive proteins | Vitronectin; VTN | 17q11.2 | Induces cell adhesion, chemotaxis |
| Thrombospondin I; THBS1 | 15q14 | Inhibition of angiogenesis |
| Laminin-8 | 18p11.31-p11.23 | Modulates cell contact interactions |
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