Review Article
Ghrelin, Des-Acyl Ghrelin, and Obestatin: Regulatory Roles on the Gastrointestinal Motility
Table 1
Summary of the regulatory roles of ghrelin, des-acyl ghrelin and obestatin on the gastroduodenal motility.
| | ghrelin | des-acyl ghrelin | obestatin | | Fasted state | Fed state | Fasted state | Fed state | Fasted state | Fed state |
| Stomach | | | | — | — | | Duodenum | | | — | — | — | | Hypothalamic neuron | NPY | urocortin 2 | CRF, urocortin 2 | Brain receptor | Y2, Y4 | CRF type 2 | CRF type 1, type 2 | Vagal afferent pathway | + | — | + |
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