Neonatal Thrombocytopenia after Perinatal Asphyxia Treated with Hypothermia: A Retrospective Case Control Study
Table 3
Morbidity, clinical findings, and presence of hemorrhage on neuroimaging.
Hypothermia
Control
value
OR [95% CI]
group
group
Seizures— (%)
45 (83%)
34 (74%)
.25
1.77 [0.67–4.67]
Treatment with >2 types of anticonvulsants— (%)
18 (33%)
8 (18%)
.07
2.38 [0.92–6.14]
Neonatal sepsis
3 (6%)
2 (4%)
.78
1.29 [0.20–8.10]
SGA
0 (0%)
2 (4%)
.12
∞
IVH grades II-III on cranial US— (%)
1 (2%)
1 (2%)
.92
0.87 [0.05–14.24]
Cerebral bleeding on MRI— (%)
11 (23%)
8 (23%)
.95
1.03 [0.37–2.91]
Mild
8 (17%)
5 (14%)
.64
Moderate/severe
3 (6%)
3 (9%)
.64
Type of moderate/severe hemorrhage
Subdural
0 (0%)
0 (0%)
—
Intraparenchymal
2 (4%)
2 (6%)
.74
Intraventricular
2 (4%)
1 (3%)
.76
Mortality— (%)
17 (31%)
9 (20%)
.18
1.89 [0.75–4.78]
Mechanical ventilation days*
4.8 (2.94)
3.6 (3.40)
.07
1.13 [0.99–1.28]
Hospital days*
10.7 (7.07)
10.4 (8.46)
.89
1.00 [0.95–1.06]
SGA: small for gestational age; IVH: intraventricular haemorrhage; US: ultrasound; MRI: magnetic resonance imaging; ∞: infinite (because of zero value in one group); *value given as mean (SD).