Prognostic Significance of a Scoring System Combining p16, Smoking, and Drinking Status in a Series of 131 Patients with Oropharyngeal Cancers

<div>Evaluation of the p16 level in oropharyngeal tumors and association with survivals. (a) Assessment of p16 positivity in OSCC patients by immunohistochemistry. High p16 immunostaining corresponding to a transcriptionally active HPV infection (p16+). (b) Evaluation of RFS and OS regarding p16 status. Patients with p16+ tumors (<i>n</i> = 36) have a significant longer RFS (HR: 3.6, 95% CI: 1.4–9.3) and OS (HR: 4.3, 95% CI: 1.7–10.9) compared to p16− tumors (<i>n</i> = 88).</div>

International Journal of Otolaryngology

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Figure 1

Figure 1: Prognostic Significance of a Scoring System Combining p16, Smoking, and Drinking Status in a Series of 131 Patients with Oropharyngeal Cancers 

Figure 1 | Prognostic Significance of a Scoring System Combining p16, Smoking, and Drinking Status in a Series of 131 Patients with Oropharyngeal Cancers 