Review Article
Clinical Outcomes of Gamma Knife Radiosurgery in the Treatment of Patients with Trigeminal Neuralgia
Table 2
Clinical outcomes of patients undergoing multiple Gamma Knife treatments.
| Author (year) | Clinical evaluation method | GKRS max retreatment dose (Gy) | Study endpoints | Results |
| | | | BNI score I | 47.6% | Gellner et al. [32] (2008) | BNI | Mean: 74.3 | BNI score II | 28.6% | | | | BNI score III | 23.8% |
| | | | BNI score I | 34% | | | | BNI score II | 17% | | | | BNI score IIIa | 6% | Huang et al. [29] (2010) | BNI | Mean: 49 | BNI score IIIb | 8% | 1-y pain control rate | 74% | | | | 2-y pain control rate | 71% | | | | 3-y pain control rate | 66% | | | | Facial numbness | 17% |
| | | | Excellent pain relief | 46% | | | | Good pain relief | 24% | Aubuchon et al. [31] (2010) | EGFP | Mean: 84.4 | Fair pain relief | 14% | | | | Poor pain relief | 16% | | | | Trigeminal nerve dysfunction | 57% |
| | | | Excellent pain relief | 43% | Huang et al. [28] (2006) | EGFP | Mean: 52 | Good pain relief | 18% | Fair pain relief | 7% | | | | Facial numbness | 36% |
| | | | Marseille class I-II | 43.5% | Kimball et al. [27] (2010) | Marseille | 70 | Marseille class III-IV | 13% | Marseille class V | 43.5% | | | | Facial numbness | 46% |
|
|
BNI: Barrow Neurological Institute; EGFP: excellent-good-fair-poor; GKRS: Gamma Knife radiosurgery.
|