Research Article
A Comparison of Urine Dilution Ability between Adult Dominant Polycystic Kidney Disease, Other Chronic Kidney Diseases, and Healthy Control Subjects: A Case-Control Study
Table 3
Kidney tubular function during urine dilution test in patients with adult dominant polycystic kidney disease (ADPKD), patients with non-ADPKD kidney disease (non-ADPKD), and healthy control subjects (controls).
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An oral water load of 20 ml/body weight was given immediately after period 2. Urine was collected in seven periods. Period 1 (24 hours): from 07.30 AM the day before arrival to the laboratory to 07.30 AM on the examination day. Period 2 (one hour): 07.30–08.30 AM. Period 3 one hour): 08.30–09.30 AM. Period 4 (one hour): 09.30–11.30 AM. Period 5 (one hour): 10.30–11.30 AM. Period 6 (one hour): 11.30–00.30 PM. Period 7 (on hour): 00.30–01.30 PM. A general linear model with Greenhouse-Geisser correction was used for comparison within and between the three groups. Values represent mean ± SD or median with 25% and 75% percentiles in brackets ∗ between ADPKD or Non-ADPKD patients and controls. # between ADPKD and Non-ADPKD patients. CCr = creatinine clearance. Alb = albumin. FENa = fractional excretion of sodium. U-ENaC = urinary epithelial sodium channel. |