Variation in APOL1 Contributes to Ancestry-Level Differences in HDLc-Kidney Function Association
Table 1
Participant characteristics by cohort1.
Cohort
West Africans (WA)
African Americans (AA)
Han Chinese (HC)
Men
Women
Men
Women
Men
Women
N
618 (41%)
879 (59%)
602 (39%)
937 (61%)
571 (52%)
529 (48%)
Age (yrs)
40.4 (15.7)
40.7 (14.2)
43.6 (13.0)
43.0 (13.7)
52.5 (9.8)
51.3 (9.0)
Current smoker (%)
49 (8%)
14 (2%)
368 (61%)
409 (44%)
200 (35%)
19 (4%)
Former smoker (%)
118 (19%)
12 (1%)
72 (12%)
108 (12%)
70 (12%)
0 (0%)
Regular alcohol intake (%)
428 (69%)
468 (53%)
480 (80%)
650 (69%)
455 (80%)
105 (20%)
BMI (kg/m2)
23.7 (4.2)
27.0 (6.4)
28.5 (7.3)
31.4 (8.8)
24.6 (3.3)
23.4 (2.8)
Hypertension (%)
204 (33%)
306 (35%)
247 (41%)
360 (38%)
266 (47%)
166 (31%)
Total cholesterol (mg/dL)2
169.0 (61.5)
182.5 (61.0)
182.0 (56.0)
188.5 (52.5)
187.5 (46.8)
185.6 (41.4)
HDL (mg/dL)2
39.0 (17.0)
42.0 (19.0)
48.0 (20.0)
54.0 (21.0)
52.6 (19.7)
53.5 (19.7)
Triglycerides (mg/dL)2
75.0 (40.0)
73.0 (41.0)
91.0 (61.0)
81.5 (49.5)
124.0 (97.4)
97.4 (61.1)
Creatinine (mg/dL)
1.06 (0.23)
0.80 (0.20)
1.04 (0.36)
0.84 (0.44)
0.87 (0.36)
0.63 (0.16)
eGFR (mL/min/1.73 m)
105.2 (26.1)
109.4 (27.3)
104.6 (20.9)
104.4 (24.4)
98.1 (13.5)
103.0 (14.2)
1Shown are means (standard deviations) or N (percentages), except where indicated.
2Median (Interquartile Range) reported due to non-normality of trait.