Synthesis and Spectroscopic and Antimicrobial Studies of Schiff Base Metal Complexes Derived from 2-Hydroxy-3-methoxy-5-nitrobenzaldehyde

Table 2

(a) Antibacterial activity of Schiff bases and their metal complexes. (b) Antifungal activity of Schiff base ligands and their metal complexes.

(a)

Minimal inhibition concentration (MIC) (g/mL)
Sr. number	Ligand/complex	E. coli	P. aeruginosa	S. aureus	S. pyogenes
		MTCC-443	MTCC-441	MTCC-96	MTCC-442
1	MPM	250	250	250	250
2	FPM	250	100	250	250
3	[Cu(MPM)2]	50	100	150	100
4	[Ni(MPM)2]	500	500	100	250
5	[Cu(FPM)2]	125	250	250	100
6	[Ni(FPM)2]	250	100	50	125
Standard drugs
1	Ampicillin	100	100	250	100
2	Chloramphenicol	50	50	50	50

(b)

Minimal inhibition concentration (MIC) (g/mL)
Sr. number	Ligand/complex	C. albicans	A. niger	A. clavatus
		MTCC-227	MTCC-282	MTCC-1323
1	MPM	1000	100	500
2	FPM	250	250	250
3	[Cu(MPM)2]	500	100	500
4	[Ni(MPM)2]	100	100	250
5	[Cu(FPM)2]	250	250	100
6	[Ni(FPM)2]	100	100	250
Standard drugs
1	Nystatin	100	100	100
2	Griseofulvin	500	100	100