Research Article
Synthesis and Spectroscopic and Antimicrobial Studies of Schiff Base Metal Complexes Derived from 2-Hydroxy-3-methoxy-5-nitrobenzaldehyde
Table 2
(a) Antibacterial activity of Schiff bases and their metal complexes. (b) Antifungal activity of Schiff base ligands and their metal complexes.
(a) |
| Minimal inhibition concentration (MIC) (g/mL) | Sr. number | Ligand/complex | E. coli | P. aeruginosa | S. aureus | S. pyogenes | MTCC-443 | MTCC-441 | MTCC-96 | MTCC-442 |
| 1 | MPM | 250 | 250 | 250 | 250 | 2 | FPM | 250 | 100 | 250 | 250 | 3 | [Cu(MPM)2] | 50 | 100 | 150 | 100 | 4 | [Ni(MPM)2] | 500 | 500 | 100 | 250 | 5 | [Cu(FPM)2] | 125 | 250 | 250 | 100 | 6 | [Ni(FPM)2] | 250 | 100 | 50 | 125 |
| Standard drugs | 1 | Ampicillin | 100 | 100 | 250 | 100 | 2 | Chloramphenicol | 50 | 50 | 50 | 50 |
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(b) |
| Minimal inhibition concentration (MIC) (g/mL) | Sr. number | Ligand/complex | C. albicans | A. niger | A. clavatus | MTCC-227 | MTCC-282 | MTCC-1323 |
| 1 | MPM | 1000 | 100 | 500 | 2 | FPM | 250 | 250 | 250 | 3 | [Cu(MPM)2] | 500 | 100 | 500 | 4 | [Ni(MPM)2] | 100 | 100 | 250 | 5 | [Cu(FPM)2] | 250 | 250 | 100 | 6 | [Ni(FPM)2] | 100 | 100 | 250 |
| Standard drugs | 1 | Nystatin | 100 | 100 | 100 | 2 | Griseofulvin | 500 | 100 | 100 |
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