Synthesis and Characterization of Biologically Active 10-Membered Tetraazamacrocyclic Complexes of Cr(III), Mn(III), and Fe(III)

Table 2

Minimum Inhibitory Concentration (MIC) shown by complexes against test bacteria by using agar dilution assay. (—) No activity, a: Bacillus cereus (MTCC 1272); b: Staphylococcus aureus (MTCC 1144); c: Escherichia coli (MTCC 739); d: Salmonella typhi (MTCC 733); Cefaclor and Linezolid are standard antibiotics.

Serial no.	Complexes	MIC (𝜇g/mL)
		a	b	c	d
(1)	[Cr(C6H8N4O2)Cl]Cl2	32	32	8	64
(2)	[Cr(C6H8N4O2)(NO3)](NO3)2	—	—	64	>128
(3)	[Cr(C6H8N4O2)(OAc)](OAc)2	8	64	64	32
(4)	[Mn(C6H8N4O2)(OAc)](OAc)2	64	>128	16	64
(5)	[Fe(C6H8N4O2)Cl]Cl2	>128	64	64	>128
(6)	[Fe(C6H8N4O2)(NO3)](NO3)2	32	4	64	>128
(7)	[Fe(C6H8N4O2)(OAc)](OAc)2	>128	64	>128	32
	Cefaclor	8	2	8	16
	Linezolid	4	4	16	32