Terminalia catappa Extract Palliates Redox Imbalance and Inflammation in Diabetic Rats by Upregulating Nrf-2 Gene

Table 5

PASS-predicted T2DM-induced oxidative stress activity of major T. catappa aqueous leaf extract phytoconstituents.

Pa	Pi	Activity
9-Oxabicyclo[3.3.1]nonane-2,6-diol
0.881	0.003	Ribulose-phosphate 3-epimerase inhibitor
0.855	0.008	HIF1A expression inhibitor
0.809	0.008	JAK2 expression inhibitor
0.802	0.009	GST A substrate
0.798	0.012	NADPH peroxidase inhibitor
0.768	0.016	Glucose oxidase inhibitor
1,2,3-Benzenetriol
0.907	0.003	NADPH peroxidase inhibitor
0.898	0.003	JAK2 expression inhibitor
0.892	0.004	Glucose oxidase inhibitor
0.858	0.004	Ribulose-phosphate 3-epimerase inhibitor
0.854	0.004	Bisphosphoglycerate phosphatase inhibitor
0.787	0.011	GST A substrate
0.711	0.004	GST M substrate