Terminalia catappa Extract Palliates Redox Imbalance and Inflammation in Diabetic Rats by Upregulating Nrf-2 Gene

Table 3

Effect of T. catappa aqueous extract treatment on other biochemical parameters in HFD/STZ-induced diabetic rats.

	Normal	Diabetic	Glibenclamide	400 TCA	800 TCA
Plasma glucose (mg/dL)	101.42 ± 14.10^a	257.06 ± 15.04^d	114.62 ± 13.13^a	158.51 ± 11.42^c	126.32 ± 14.51^b
TNF-α (pg/mL)
Plasma	9.37 ± 1.56^a	15.87 ± 1.58^d	11.27 ± 1.60^c	12.66 ± 3.70^c	10.69 ± 1.11^b
Liver	3.37 ± 0.65^a	19.54 ± 1.40^c	11.83 ± 22.10^b	10.21 ± 16.86^b	6.03 ± 10.98^a
Kidney	9.92 ± 1.36	9.39 ± 2.67	9.91 ± 1.88	10.33 ± 1.01	8.47 ± 1.73
IL-6 (pg/mL)
Plasma	28.38 ± 6.77^a	211.52 ± 27.00^e	94.22 ± 8.06^c	147.05 ± 14.97^d	59.39 ± 10.28^b
Liver	7.75 ± 0.88^a	15.85 ± 1.12^e	13.99 ± 4.62^d	9.36 ± 1.78^c	7.39 ± 1.41^b
Kidney	5.36 ± 0.32	7.74 ± 0.85	6.45 ± 1.87	6.35 ± 0.36	5.91 ± 1.49
Total protein (mg/mL)
Plasma	539.60 ± 14.09^c	463.49 ± 2.07^a	501.81 ± 13.75^b	509.76 ± 13.59^b	532.23 ± 13.16^c
Liver	154.33 ± 13.49^c	109.35 ± 3.18^a	138.45 ± 4.22^b	132.31 ± 5.04^b	137.11 ± 4.99^b
Kidney	124.99 ± 8.12^d	99.55 ± 1.49^a	120.39 ± 0.91^c	109.80 ± 1.90^b	125.41 ± 0.93^d
Erythrocyte	133.60 ± 6.38^c	95.08 ± 2.85^a	127.62 ± 10.91^b	123.33 ± 4.24^b	135.71 ± 3.05^c

Data are represented as mean ± SEM (n = 6). Values with different superscripts across a row are significantly different, while those without superscripts are not significantly different at .