Morphological Characteristics of the Thymus and Spleen and the Subpopulation Composition of Lymphocytes in Peripheral Blood during Systemic Inflammatory Response in Male Rats with Different Resistance to Hypoxia

Figure 2

Morphological changes in the lungs of tolerant- and susceptible-to-hypoxia male Wistar rats after 3, 6, and 24 hours of LPS administration. Hematoxylin and eosin staining. Original magnification: ((a)-(h)) 1000x. Neutrophils are marked via arrows. (a) Tolerant-to-hypoxia rat, control group; few neutrophils in the field of view. (b) Susceptible-to-hypoxia rat, control group; thin interalveolar septa without neutrophils in the field of view. (c) Tolerant-to-hypoxia rat, 3 h LPS; interalveolar septa with neutrophils. (d) Susceptible-to-hypoxia rat, 3 h LPS; pronounced neutrophil infiltration in thickened interalveolar septa. (e) Tolerant-to-hypoxia rat, 6 h LPS; mild neutrophil infiltration in thickened interalveolar septa. (f) Susceptible-to-hypoxia rat, 6 h LPS; high number of neutrophils in thickened interalveolar septa. (g) Tolerant-to-hypoxia rat, 24 h LPS; interalveolar septa with few neutrophils. (h) Susceptible-to-hypoxia rat, 24 h LPS; interalveolar septa with neutrophils.

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