Obesity Related Alterations in Plasma Cytokines and Metabolic Hormones in Chimpanzees
Figure 1
Measurement of cytokines by multiplex cytokine bead array (CBA) in plasma of lean (N #28), overweight (N #10), and obese (N #10) chimpanzees using Bio-Rad 200, Luminex technology. The results are expressed as pg/mL concentration and are an average of two distinct experiments. (a) Shows proinflammatory cytokines, (b) anti-inflammatory cytokines, and (c) chemokine. See method section for experiment details. Comparison between groups of chimpanzees was done by one-way analysis of variance with the Kruskal-Wallis test and Gaussian approximation with Dunn’s multiple comparison tests. Data are presented as group means ± SD. Only differences with a probability less than 0.05 were considered to be significant. All statistical analyses were conducted using GraphPad Prism 6.00 (GraphPad Software, San Diego, California, USA).
