Long-Lasting Effect of Infant Rats Endotoxemia on Heat Shock Protein 60 in the Pancreatic Acinar Cells: Involvement of Toll-Like Receptor 4
Figure 7
Analysis of DNA fragmentation pattern in the adult rat pancreatic acinar cells under basal conditions (lane 1), stimulated in vitro by caerulein at the dose of 10−8 M (lane 2), treated in the infant animals by lipopolysaccharide (Escherichia coli) at the doses of 15 mg/kg/day × 5 days + caerulein 10−8 M (lane 3), 10 mg/kg/day × 5 days + caerulein 10−8 M (lane 4), and 5 mg/kg/day × 5 days + caerulein 10−8 M (lane 5) after 5 hours of incubation. All presented results were obtained in 4 consecutive experiments and are representative of the observed phenomenon.
