|
Tissue type | Effect | Species | Source |
|
EC | Autoinduces IL-19 expression | h | [40] |
Activates STAT3, Rac1, and MAPK p44/42 | h | [40] |
Increases EC proliferation | h | [40] |
Increases EC spreading, and migration | h | [40] |
Proangiogenic (increase tube, microvessel formation) | m | [40] |
Inhibits HuR nucleocytoplasmic translocation | h | [67] |
|
VSMC | Inhibits proliferation, hyperplasia | h, r | [41] |
Autoinduces IL-19 expression | h | [41] |
STAT3 phosphorylation, translocation | h | [41] |
Increases SOCS5 expression | h | [41] |
Inhibits MAPKs (p44/42, p38) | h | [41] |
Decreases inflammatory, proliferative proteins, and mRNAs | h | [68] |
Decreases HuR protein abundance | h | [68] |
Inhibits HuR nucleocytoplasmic translocation | h | [68] |
Decreases ARE-bearing mRNA stability | h | [68] |
Inhibits PKCα activation | h | [68] |
Inhibits migration, spreading | h | [69] |
Inhibits activation of MLC, cofilin, Hsp70, Rac1, and RhoA | h | [69] |
STAT3-dependent increase heme oxygenase-1 expression | h | [70] |
Decreases ROS in vitro and in vivo | h, m | [70] |
Inhibits apoptosis | h | [70] |
|