Neurokinin-1 Receptor Antagonist Treatment in Polymicrobial Sepsis: Molecular Insights
Figure 6
Effect of GR159897 administration 1 hour after CLP on lung (a) neutrophil infiltration (MPO), (b) CXCL-2, (c) CCL-2, (d) IL-1 and (e) IL-6 levels. Results shown are the mean S.E.M ( 6–9 in each group). “CLP + vehicle” and “CLP + SR140333” represent the groups that received vehicle and SR140333 treatment, respectively, 1 hour after CLP. when vehicle-treated CLP animals were compared with sham group animals. CLP: cecal ligation and puncture; IL: interleukin; MPO: myeloperoxidase.